CRHR1 Antibody

Product Specifications

Background

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene.

NCBI Gene ID

1394

Swiss Prot

P34998

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 24-120 of human CRHR1 (NP_001138618.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Obesity, Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 60kDa

Fragment

IgG

Symbol

CRHR1

Positive Control 2

SH-SY5Y

Positive Control 3

HT-29

Positive Control 4

HeLa

Positive Control 5

Mouse brain

Positive Control 6

Mouse liver

NCBI Official Name

Corticotropin releasing hormone receptor 1

NCBI Organism

Homo sapiens

Other Product Names

CRHR1, corticotropin releasing hormone receptor 1, CRF-R, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f, corticotropin releasing hormone receptor variant 1h, seven transmembrane helix receptor, CRFR