PITRM1 Antibody
Product Specifications
Background
The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
NCBI Gene ID
10531
Swiss Prot
Q5JRX3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 758-1037 of human PITRM1 (NP_055704.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
NIH/3T3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 117kDa
Fragment
IgG
Symbol
PITRM1
Positive Control 2
A-549
Positive Control 3
MCF7
Positive Control 4
U-87MG
Positive Control 5
Mouse liver
Positive Control 6
Mouse heart
NCBI Official Name
Presequence protease, mitochondrial
NCBI Organism
Homo sapiens
Other Product Names
Presequence protease, mitochondrial, hPreP, 3424-, Pitrilysin metalloproteinase 1, Metalloprotease 1, hMP1, PITRM1, KIAA1104, MP1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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