NR1H4 Antibody
Product Specifications
Background
This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.
NCBI Gene ID
9971
Swiss Prot
Q96RI1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 207-476 of human NR1H4 (NP_001193908.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 59kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
NR1H4
Positive Control 2
HeLa
Positive Control 3
HepG2
Positive Control 4
293T
NCBI Official Name
Nuclear receptor subfamily 1, group H, member 4
NCBI Organism
Homo sapiens
Other Product Names
NR1H4, BAR, FXR, HRR1, HRR-1, RIP14
Tested Applications
WB
Physical Properties
Liquid
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