MRPS22 Antibody
Product Specifications
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq.
NCBI Gene ID
56945
Swiss Prot
P82650
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human MRPS22 (NP_064576.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-508
Calculated Molecular Weight
Observed: 41kDa
Fragment
IgG
Symbol
MRPS22
Positive Control 2
HeLa
Positive Control 3
SW480
Positive Control 4
A-549
Positive Control 5
MCF7
Positive Control 6
Jurkat
NCBI Official Name
Mitochondrial ribosomal protein S22
NCBI Organism
Homo sapiens
Other Product Names
C3orf5, COXPD5, GIBT, GK002, MRP-S22, ODG7, RPMS22, 28S ribosomal protein S22, mitochondrial, S22mt, mitochondrial small ribosomal subunit protein mS22
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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