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SHOX2 Antibody

Product Specifications

Background

This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

6474

Swiss Prot

O60902

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 96-355 of human SHOX2 (NP_003021.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Affinity purification

Positive Control

NCI-H460

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=23-501

Calculated Molecular Weight

Observed: 30kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

SHOX2

Positive Control 2

Mouse skeletal muscle

Positive Control 3

Mouse liver

NCBI Official Name

Short stature homeobox 2

NCBI Organism

Homo sapiens

Other Product Names

SHOX2, OG12, OG12X, OGI2X, SHOT

Tested Applications

WB

Physical Properties

Liquid

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