NDUFA12 Antibody

Product Specifications

Background

This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

55967

Swiss Prot

Q9UI09

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human NDUFA12 (NP_061326.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 17kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

NDUFA12

Positive Control 2

PC-12

Positive Control 3

HepG2

Positive Control 4

Mouse kidney

Positive Control 5

Mouse heart

Positive Control 6

Mouse testis

NCBI Official Name

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

NCBI Organism

Homo sapiens

Other Product Names

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12, 13 kDa differentiation-associated protein, Complex I-B172, CI-B172, CIB172, NADH-ubiquinone oxidoreductase subunit B172, NDUFA12, DAP13