ARFGAP3 Antibody
Product Specifications
Background
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1) -bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
NCBI Gene ID
26286
Swiss Prot
Q9NP61
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 217-516 of human ARFGAP3 (NP_055385.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-461
Calculated Molecular Weight
Observed: 57kDa
Fragment
IgG
Symbol
ARFGAP3
Positive Control 2
Mouse pancreas
NCBI Official Name
ADP-ribosylation factor GTPase activating protein 3
NCBI Organism
Homo sapiens
Other Product Names
ARFGAP3, ADP-ribosylation factor GTPase activating protein 3, ARFGAP1, RP1-47A17.3, ADP-ribosylation factor GTPase activating protein 1, OTTHUMP00000028526
Tested Applications
WB, IHC
Physical Properties
Liquid
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