VNN2 Antibody
Product Specifications
Background
This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
NCBI Gene ID
8875
Swiss Prot
O95498
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 270-493 of human VNN2 (NP_004656.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 33kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
VNN2
Positive Control 2
Mouse brain
Positive Control 3
Rat brain
NCBI Official Name
Vanin 2
NCBI Organism
Homo sapiens
Other Product Names
FOAP-4, GPI-8vascular non-inflammatory molecule 2, Vannin 2, glycosylphosphatidyl inositol-anchored protein GPI-8pantetheinase
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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