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FZD4 Antibody

Product Specifications

Background

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

NCBI Gene ID

8322

Swiss Prot

Q9ULV1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 37-222 of human FZD4 (NP_036325.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

22Rv1

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Symbol

FZD4

Positive Control 2

SKOV3

Positive Control 3

293T

Positive Control 4

Mouse trachea

Positive Control 5

Mouse eye

NCBI Official Name

Frizzled class receptor 4

NCBI Organism

Homo sapiens

Other Product Names

FZD4, EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, MGC34390, Fz4, hFz4, CD344

Tested Applications

WB, IHC

Physical Properties

Liquid

Frequently Asked Questions

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