PRPS1 Antibody
Product Specifications
Background
This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
5631
Swiss Prot
P60891
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human PRPS1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 35kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PRPS1
Positive Control 2
U-87MG
Positive Control 3
SW620
Positive Control 4
HT-29
Positive Control 5
Mouse lung
Positive Control 6
Mouse brain
NCBI Official Name
Ribose-phosphate pyrophosphokinase 1
NCBI Organism
Homo sapiens
Other Product Names
Ribose-phosphate pyrophosphokinase 1, PPRibP, Phosphoribosyl pyrophosphate synthase I, PRS-I, PRPS1
Tested Applications
WB
Physical Properties
Liquid
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