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OXCT1 Antibody, KO Validated

Product Specifications

Background

This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.

NCBI Gene ID

5019

Swiss Prot

P55809

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 261-520 of human OXCT1 (NP_000427.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Antibody is Knockout validated.

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

BT-474

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 56kDa

Fragment

IgG

Symbol

OXCT1

Positive Control 2

HeLa

Positive Control 3

Jurkat

Positive Control 4

293T

Positive Control 5

Mouse kidney

Positive Control 6

Mouse heart

NCBI Official Name

3-oxoacid CoA transferase 1

NCBI Organism

Homo sapiens

Other Product Names

OXCT1, OXCT, SCOT

Tested Applications

WB, IHC

Physical Properties

Liquid

Curated Selection

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