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CETN3 Antibody

Product Specifications

Background

The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

1070

Swiss Prot

O15182

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human CETN3 (NP_004356.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

MCF7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 20kDa

Fragment

IgG

Symbol

CETN3

Positive Control 2

Jurkat

Positive Control 3

293T

Positive Control 4

Mouse testis

Positive Control 5

Mouse spleen

Positive Control 6

Mouse lung

NCBI Official Name

Centrin 3

NCBI Organism

Homo sapiens

Other Product Names

CDC31, CEN3, centrin-3, CDC31 yeast homolog, EF-hand superfamily member, centrin, EF-hand protein, 3 (CDC31 homolog, yeast)

Tested Applications

WB, IHC

Physical Properties

Liquid

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