CDH11 Antibody
Product Specifications
Background
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
NCBI Gene ID
1009
Swiss Prot
P55287
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 637-796 of human CDH11 (NP_001788.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 120kDa
Fragment
IgG
Symbol
CDH11
Positive Control 2
A-549
Positive Control 3
HT-29
Positive Control 4
SKOV3
Positive Control 5
Mouse lung
Positive Control 6
Mouse spleen
NCBI Official Name
Cadherin 11, type 2, OB-cadherin (osteoblast)
NCBI Organism
Homo sapiens
Other Product Names
CDH11, osteoblast cadherin, OSF-4, OB-cadherin, OB, CDHOB, cadherin-11, cadherin 11, type 2, OB-cadherin (osteoblast), CAD11
Tested Applications
WB, IHC
Physical Properties
Liquid
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
