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CDH11 Antibody

Product Specifications

Background

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

NCBI Gene ID

1009

Swiss Prot

P55287

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 637-796 of human CDH11 (NP_001788.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=23-407

Calculated Molecular Weight

Observed: 120kDa

Fragment

IgG

Symbol

CDH11

Positive Control 2

A-549

Positive Control 3

HT-29

Positive Control 4

SKOV3

Positive Control 5

Mouse lung

Positive Control 6

Mouse spleen

NCBI Official Name

Cadherin 11, type 2, OB-cadherin (osteoblast)

NCBI Organism

Homo sapiens

Other Product Names

CDH11, osteoblast cadherin, OSF-4, OB-cadherin, OB, CDHOB, cadherin-11, cadherin 11, type 2, OB-cadherin (osteoblast), CAD11

Tested Applications

WB, IHC

Physical Properties

Liquid

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