ANAPC2 Antibody
Product Specifications
Background
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.
NCBI Gene ID
29882
Swiss Prot
Q9UJX6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human ANAPC2 (NP_037498.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
Mouse brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 102kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ANAPC2
Positive Control 2
Mouse kidney
Positive Control 3
Rat brain
Positive Control 4
Rat kidney
NCBI Official Name
Adenomatosis polyposis coli 2
NCBI Organism
Homo sapiens
Other Product Names
APC2, APCL
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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