LEPREL2 Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.
NCBI Gene ID
10536
Swiss Prot
Q8IVL6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 487-736 of human LEPREL2 (NP_055077.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
22Rv1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 82kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
LEPREL2
Positive Control 2
NIH/3T3
Positive Control 3
Mouse skeletal muscle
NCBI Official Name
Prolyl 3-hydroxylase 3
NCBI Organism
Homo sapiens
Other Product Names
GRCB, HSU47926, LEPREL2, prolyl 3-hydroxylase 3, gene rich cluster, B, leprecan-like 2, procollagen-proline 3-dioxygenase, protein B
Tested Applications
WB
Physical Properties
Liquid
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