RDH5 Antibody

Product Specifications

Background

This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.

NCBI Gene ID

5959

Swiss Prot

Q92781

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 24-318 of human RDH5 (NP_002896.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 38kDa

Fragment

IgG

Symbol

RDH5

Positive Control 2

BT-474

Positive Control 3

Mouse liver

Positive Control 4

Mouse kidney

Positive Control 5

Rat liver

NCBI Official Name

Retinol dehydrogenase 5 (11-cis/9-cis)

NCBI Organism

Homo sapiens

Other Product Names

RDH5, short chain dehydrogenase/reductase family 9C, SDR9C5, retinol dehydrogenase 5 (11-cis/9-cis), retinol dehydrogenase 5 (11-cis and 9-cis), retinol dehydrogenase 1, RDH1, HSD17B9, FLJ97089, FLJ39337, 9-cis-retinol specific dehydrogenase, 11-cis RDH