HMGCL Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
3155
Swiss Prot
P35914
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human HMGCL (NP_000182.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 30kDa
Fragment
IgG
Symbol
HMGCL
Positive Control 2
SKOV3
Positive Control 3
BT-474
Positive Control 4
MCF7
Positive Control 5
Mouse liver
Positive Control 6
Mouse kidney
NCBI Official Name
3-hydroxymethyl-3-methylglutaryl-CoA lyase
NCBI Organism
Homo sapiens
Other Product Names
HMGCL, HL
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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