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NDUFS3 Antibody, KO Validated

Product Specifications

Background

This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I) . Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.

NCBI Gene ID

4722

Swiss Prot

O75489

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 37-264 of human NDUFS3 (NP_004542.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Antibody is Knockout validated.

Field of Research

Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

MCF-7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 30kDa

Fragment

IgG

Symbol

NDUFS3

Positive Control 2

SW620

Positive Control 3

HepG2

Positive Control 4

Mouse kidney

Positive Control 5

Mouse liver

Positive Control 6

Mouse heart

NCBI Official Name

NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)

NCBI Organism

Homo sapiens

Other Product Names

NDUFS3, NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)

Tested Applications

WB, IHC

Physical Properties

Liquid

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