ORC6 Antibody

Product Specifications

Background

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

NCBI Gene ID

23594

Swiss Prot

Q9Y5N6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human ORC6 (NP_055136.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 28kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ORC6

Positive Control 2

SW620

Positive Control 3

PC-3

Positive Control 4

HeLa

Positive Control 5

Mouse liver

Positive Control 6

Mouse brain

NCBI Official Name

Origin recognition complex, subunit 6

NCBI Organism

Homo sapiens

Other Product Names

ORC6L, origin recognition complex, subunit 6 homolog-like (yeast), ORC6, origin recognition complex subunit 6, subunit 6-like (yeast), subunit 6 (yeast homolog) -like, ORC6L