MAP4K5 Antibody

Product Specifications

Background

This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

NCBI Gene ID

11183

Swiss Prot

Q9Y4K4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 300-480 of human MAP4K5 (NP_006566.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

MCF7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 120kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

MAP4K5

Positive Control 2

A-549

Positive Control 3

Jurkat

Positive Control 4

Mouse brain

Positive Control 5

Mouse spleen

Positive Control 6

Rat brain

NCBI Official Name

Mitogen-activated protein kinase kinase kinase kinase 5

NCBI Organism

Homo sapiens

Other Product Names

GCKR, KHS, KHS1, MAPKKKK5, mitogen-activated protein kinase kinase kinase kinase 5, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5, MEKKK 5, germinal center kinase-related, kinase homologous to SPS1/STE20