WHSC1 Antibody
Product Specifications
Background
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t (4;14) (p16.3; q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
NCBI Gene ID
7468
Swiss Prot
O96028
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human WHSC1 (NP_579877.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 80kDa, 152kDa
Fragment
IgG
Symbol
NSD2
Positive Control 2
HepG2
Positive Control 3
SW620
Positive Control 4
Mouse brain
Positive Control 5
Mouse spleen
NCBI Official Name
Wolf-Hirschhorn syndrome candidate 1
NCBI Organism
Homo sapiens
Other Product Names
WHSC1, WHS, NSD2, TRX5, MMSET, REIIBP
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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