STX1A Antibody
Product Specifications
Background
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) -Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc) . Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
6804
Swiss Prot
Q16623
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
A synthetic peptide of human STX1A
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Fragment
IgG
Symbol
STX1A
NCBI Official Name
Syntaxin 1A (brain)
NCBI Organism
Homo sapiens
Other Product Names
STX1, HPC-1, P35-1, SYN1A, STX1, Neuron-specific antigen HPC-1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Frequently Asked Questions
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