AURKC Antibody

Product Specifications

Background

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

6795

Swiss Prot

Q9UQB9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human AURKC

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 36kDa

Fragment

IgG

Symbol

AURKC

Positive Control 2

293T

Positive Control 3

SW620

Positive Control 4

BT-474

Positive Control 5

Mouse testis

Positive Control 6

Mouse ovary

NCBI Official Name

Aurora kinase C

NCBI Organism

Homo sapiens

Other Product Names

AURKC, STK13, serine/threonine kinase 13 (aurora/IPL1-like), aurora-C, aurora/IPL1-related kinase 3, aurora/IPL1/EG2 protein 2, aurora kinase C, AurC, ARK3, AIK3, AIE2, AIRK3