FCGR3B Antibody

Product Specifications

Background

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG) . The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.

NCBI Gene ID

2215

Swiss Prot

O75015

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FCGR3B (NP_000561.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 26kDa/46kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

FCGR3B

Positive Control 2

Raji

Positive Control 3

U-937

Positive Control 4

THP-1

Positive Control 5

Mouse liver

Positive Control 6

Mouse spleen

NCBI Official Name

Low affinity immunoglobulin gamma Fc region receptor III-B

NCBI Organism

Homo sapiens

Other Product Names

Low affinity immunoglobulin gamma Fc region receptor III-B, Fc-gamma RIII-beta, Fc-gamma RIII, Fc-gamma RIIIb, FcRIII, FcRIIIb, FcR-10, IgG Fc receptor III-1, CD16b, FCGR3B, CD16B, FCG3, FCGR3, IGFR3