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EYA3 Antibody

Product Specifications

Background

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.

NCBI Gene ID

2140

Swiss Prot

Q99504

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human EYA3 (NP_001981.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 63kDa

Fragment

IgG

Symbol

EYA3

Positive Control 2

293T

Positive Control 3

HT-29

Positive Control 4

Mouse liver

Positive Control 5

Mouse eye

Positive Control 6

Rat eye

NCBI Official Name

Eyes absent homolog 3 (Drosophila)

NCBI Organism

Homo sapiens

Other Product Names

EYA3

Tested Applications

WB, IHC

Physical Properties

Liquid

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