CPN1 Antibody
Product Specifications
Background
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.
NCBI Gene ID
1369
Swiss Prot
P15169
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 209-458 of human CPN1 (NP_001299.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 52kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CPN1
Positive Control 2
Raji
Positive Control 3
Mouse liver
Positive Control 4
Mouse pancreas
Positive Control 5
Rat brain
NCBI Official Name
Carboxypeptidase N, polypeptide 1
NCBI Organism
Homo sapiens
Other Product Names
CPN1, CPN, FLJ40792, SCPN
Tested Applications
WB
Physical Properties
Liquid
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