ATP1A1 Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta) . The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
476
Swiss Prot
P05023
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ATP1A1 (NP_000692.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-248
Calculated Molecular Weight
Observed: 115kDa
Fragment
IgG
Symbol
ATP1A1
NCBI Official Name
Sodium/potassium-transporting ATPase subunit alpha-1
NCBI Organism
Homo sapiens
Other Product Names
Sodium/potassium-transporting ATPase subunit alpha-1, Na (+) /K (+) ATPase alpha-1 subunit, 3.6.3.9, Sodium pump subunit alpha-1, ATP1A1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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