ADRA1B Antibody
Product Specifications
Background
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
NCBI Gene ID
147
Swiss Prot
P35368
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human ADRA1B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-243
Calculated Molecular Weight
Observed: 50kDa
Fragment
IgG
Symbol
ADRA1B
Positive Control 2
Jurkat
Positive Control 3
MCF7
Positive Control 4
HepG2
Positive Control 5
Mouse heart
NCBI Official Name
Adrenoceptor alpha 1B
NCBI Organism
Homo sapiens
Other Product Names
ADRA1B, adrenergic, alpha-1B-, receptor, ADRA1, ALPHA1BAR, OTTHUMP00000160844, alpha-1B adrenergic receptor, alpha-1B adrenoceptor, alpha-1B adrenoreceptor, alpha-1B-adrenergic receptor
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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