ADRA1B Antibody

Product Specifications

Background

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

NCBI Gene ID

147

Swiss Prot

P35368

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human ADRA1B

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

HL-60

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 50kDa

Fragment

IgG

Symbol

ADRA1B

Positive Control 2

Jurkat

Positive Control 3

MCF7

Positive Control 4

HepG2

Positive Control 5

Mouse heart

NCBI Official Name

Adrenoceptor alpha 1B

NCBI Organism

Homo sapiens

Other Product Names

ADRA1B, adrenergic, alpha-1B-, receptor, ADRA1, ALPHA1BAR, OTTHUMP00000160844, alpha-1B adrenergic receptor, alpha-1B adrenoceptor, alpha-1B adrenoreceptor, alpha-1B-adrenergic receptor