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TM2D1 Antibody

Product Specifications

Background

The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene.

NCBI Gene ID

83941

Swiss Prot

Q9BX74

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 38-207 of human TM2D1 (NP_114416.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

NCI-H460

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=23-219

Calculated Molecular Weight

Observed: 30kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

TM2D1

Positive Control 2

HeLa

Positive Control 3

Mouse kidney

Positive Control 4

Rat brain

NCBI Official Name

TM2 domain containing 1

NCBI Organism

Homo sapiens

Other Product Names

BBP, TM2 domain-containing protein 1, Beta-amyloid peptide binding protein, amyloid-beta-binding protein, beta-amyloid-binding protein, hBBP

Tested Applications

WB

Physical Properties

Liquid

Curated Selection

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