ANKS1B Antibody

Product Specifications

Background

This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t (1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.

NCBI Gene ID

56899

Swiss Prot

Q7Z6G8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 261-510 of human ANKS1B (NP_858056.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 80kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ANKS1B

Positive Control 2

Mouse liver

NCBI Official Name

Ankyrin repeat and sterile alpha motif domain-containing protein 1B

NCBI Organism

Homo sapiens

Other Product Names

Ankyrin repeat and sterile alpha motif domain-containing protein 1B, Amyloid-beta protein intracellular domain-associated protein 1, AIDA-1, E2A-PBX1-associated protein, EB-1, ANKS1B