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SQSTM1 / p62 Antibody

Product Specifications

Background

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

NCBI Gene ID

8878

Swiss Prot

Q13501

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-440 of human SQSTM1 / p62 (NP_001135770.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Autophagy, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

BT-474

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=23-162

Calculated Molecular Weight

Observed: 60kDa

Fragment

IgG

Symbol

SQSTM1

Positive Control 2

NCI-H460

Positive Control 3

HeLa

Positive Control 4

Jurkat

Positive Control 5

Mouse liver

Positive Control 6

Mouse kidney

NCBI Official Name

Sequestosome 1

NCBI Organism

Homo sapiens

Other Product Names

SQSTM1 Antibody: p60, p62, A170, OSIL, PDB3, ZIP3, p62B, ORCA, Sequestosome-1, EBI3-associated protein of 60 kDa, EBIAP

Tested Applications

WB, IHC, IF, IP

Physical Properties

Liquid

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