B3GALNT1 Antibody
Product Specifications
Background
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine) . The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5) . The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all.
NCBI Gene ID
8706
Swiss Prot
O75752
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 44-331 of human B3GALNT1 (NP_003772.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
SKOV3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-159
Calculated Molecular Weight
Observed: 45kDa
Fragment
IgG
Symbol
B3GALNT1
Positive Control 2
U-251MG
NCBI Official Name
Beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
NCBI Organism
Homo sapiens
Other Product Names
B3GALT3, GLCT3, GLOB, Gb4Cer, P, P1, beta3Gal-T3, galT3, UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1, P antigen synthase, P blood group globoside, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3 (Globoside blood group), UDP-GalNAc:betaGlcNAc beta-1,3-galactosaminyltransferase, polypeptide 1 (Globoside blood group), UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase, b3Gal-T3, beta-1,3-GalNAc-T1, beta-1,3-GalTase 3, beta-1,3-galactosyltransferase 3, beta-3-Gx-T3, brainiac1, galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase, globoside synthase, globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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