NCK2 Antibody
Product Specifications
Background
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
NCBI Gene ID
8440
Swiss Prot
O43639
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-380 of human NCK2 (NP_003572.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 43kDa
Fragment
IgG
Symbol
NCK2
Positive Control 2
Mouse lung
Positive Control 3
Rat brain
NCBI Official Name
NCK adaptor protein 2
NCBI Organism
Homo sapiens
Other Product Names
NCK2, GRB4, NCKbeta, NCK beta, Nck-2, Cytoplasmic protein NCK2, NCK adaptor protein 2
Tested Applications
WB, IHC
Physical Properties
Liquid
Frequently Asked Questions
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