SRF Antibody
Product Specifications
Background
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs) . Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
6722
Swiss Prot
P11831
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human SRF
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction, Stem Cell, Transcription
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-139
Calculated Molecular Weight
Observed: 67kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SRF
Positive Control 2
Jurkat
NCBI Official Name
Serum response factor (c-fos serum response element-binding transcription factor)
NCBI Organism
Homo sapiens
Other Product Names
SRF, MCM1
Tested Applications
WB
Physical Properties
Liquid
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