PPIB Antibody
Product Specifications
Background
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
NCBI Gene ID
5479
Swiss Prot
P23284
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 34-216 of human PPIB (NP_000933.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 24kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PPIB
Positive Control 2
22Rv1
Positive Control 3
HepG2
Positive Control 4
THP-1
Positive Control 5
Mouse liver
Positive Control 6
Mouse kidney
NCBI Official Name
Peptidylprolyl isomerase B (cyclophilin B)
NCBI Organism
Homo sapiens
Other Product Names
PPIB, CYP-S1, CYPB, MGC14109, MGC2224, SCYLP, OI9, HEL-S-39
Tested Applications
WB
Physical Properties
Liquid
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