P2RY1 Antibody
Product Specifications
Background
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
NCBI Gene ID
5028
Swiss Prot
P47900
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 274-373 of human P2RY1 (NP_002554.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
22Rv1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 42kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
P2RY1
Positive Control 2
Rat liver
Positive Control 3
Rat intestine
NCBI Official Name
Purinergic receptor P2Y, G-protein coupled, 1
NCBI Organism
Homo sapiens
Other Product Names
P2RY12, ADPG-R, HORK3, P2T (AC), P2Y (AC), P2Y (ADP), P2Y (cyc), P2Y12, SP1999, P2Y1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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