LOX Antibody
Product Specifications
Background
This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections.
NCBI Gene ID
4015
Swiss Prot
P28300
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human LOX
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 38kDa
Fragment
IgG
Symbol
LOX
Positive Control 2
Jurkat
Positive Control 3
A-431
Positive Control 4
Mouse heart
Positive Control 5
Mouse skeletal muscle
Positive Control 6
Mouse skin
NCBI Official Name
Protein-lysine 6-oxidase
NCBI Organism
Homo sapiens
Other Product Names
Protein-lysine 6-oxidase, Lysyl oxidase, LOX
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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