VEGF Receptor 2 Antibody

Product Specifications

Background

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

NCBI Gene ID

3791

Swiss Prot

P35968

Host

Rabbit

Reactivity

Rat

Immunogen

A synthetic peptide of human VEGF Receptor 2

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

Rat brain

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 152kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

KDR

NCBI Official Name

Kinase insert domain receptor (a type III receptor tyrosine kinase)

NCBI Organism

Homo sapiens

Other Product Names

Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1, CD309, KDR, FLK1, VEGFR2