IRF1 Antibody
Product Specifications
Background
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
NCBI Gene ID
3659
Swiss Prot
P10914
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human IRF1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Transcription, Inflammasomes
Purification
Affinity purification
Positive Control
NIH/3T3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-112
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Symbol
IRF1
Positive Control 2
Jurkat
Positive Control 3
SW480
Positive Control 4
HL-60
Positive Control 5
MCF7
Positive Control 6
Mouse liver
NCBI Official Name
Interferon regulatory factor 1
NCBI Organism
Homo sapiens
Other Product Names
IRF1, IRF-1, MAR
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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