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TNFRSF8 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

NCBI Gene ID

943

Swiss Prot

P28908

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide of human TNFRSF8

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=23-081

Calculated Molecular Weight

Observed: 128kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

TNFRSF8

Positive Control 2

Jurkat

Positive Control 3

H460

NCBI Official Name

Tumor necrosis factor receptor superfamily, member 8

NCBI Organism

Homo sapiens

Other Product Names

Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E

Tested Applications

WB

Physical Properties

Liquid

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