TNFRSF8 Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
NCBI Gene ID
943
Swiss Prot
P28908
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide of human TNFRSF8
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 128kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
TNFRSF8
Positive Control 2
Jurkat
Positive Control 3
H460
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 8
NCBI Organism
Homo sapiens
Other Product Names
Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E
Tested Applications
WB
Physical Properties
Liquid
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