BCS1L Antibody

Product Specifications

Background

This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Several alternatively spliced transcripts encoding two different isoforms have been described.

NCBI Gene ID

617

Swiss Prot

Q9Y276

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 33-240 of human BCS1L (NP_004319.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 48kDa

Fragment

IgG

Symbol

BCS1L

Positive Control 2

SKOV3

Positive Control 3

MCF7

Positive Control 4

HeLa

Positive Control 5

Mouse heart

Positive Control 6

Mouse liver

NCBI Official Name

BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone

NCBI Organism

Homo sapiens

Other Product Names

BCS, BCS1, BJS, FLNMS, GRACILE, Hs.6719, MC3DN1, PTD, h-BCS, h-BCS1, mitochondrial chaperone BCS1, BC1 (ubiquinol-cytochrome c reductase) synthesis-like, BCS1-like protein, mitochondrial complex III assembly