BAAT Antibody
Product Specifications
Background
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA) . Two transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
570
Swiss Prot
Q14032
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 309-418 of human BAAT (NP_001692.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 40-46kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
BAAT
Positive Control 2
BT-474
Positive Control 3
A-549
Positive Control 4
HepG2
Positive Control 5
Mouse liver
Positive Control 6
Rat liver
NCBI Official Name
Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
NCBI Organism
Homo sapiens
Other Product Names
BAAT, BACAT, BAT, FLJ20300, MGC104432
Tested Applications
WB
Physical Properties
Liquid
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