LMO1 Antibody

Product Specifications

Background

This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.

NCBI Gene ID

4004

Swiss Prot

P25800

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-156 of human LMO1 (NP_002306.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

U-251MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 14kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

LMO1

NCBI Official Name

LIM domain only 1

NCBI Organism

Homo sapiens

Other Product Names

RBTN1, RHOM1, TTG1, rhombotin-1, LIM domain only 1 (rhombotin 1), LIM domain only protein 1, LMO-1, T-cell translocation gene 1, T-cell translocation protein 1, cysteine-rich protein TTG-1