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PTK6 Antibody

Product Specifications

Background

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

5753

Swiss Prot

Q13882

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 222-451 of human PTK6 (NP_005966.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

SW480

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=22-985

Calculated Molecular Weight

Observed: 60kDa

Fragment

IgG

Symbol

PTK6

Positive Control 2

BT-474

Positive Control 3

MCF7

Positive Control 4

A-549

Positive Control 5

NIH/3T3

Positive Control 6

Mouse liver

NCBI Official Name

Protein tyrosine kinase 6

NCBI Organism

Homo sapiens

Other Product Names

BRK, Breast tumor kinaseBRK

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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