ASPSCR1 Antibody
Product Specifications
Background
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4) . This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t (X;17) (p11; q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.
NCBI Gene ID
79058
Swiss Prot
Q9BZE9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 284-553 of human ASPSCR1 (NP_076988.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=22-973
Calculated Molecular Weight
Observed: 80kDa
Fragment
IgG
Symbol
ASPSCR1
Positive Control 2
SW480
Positive Control 3
A-549
Positive Control 4
BT-474
Positive Control 5
Mouse liver
Positive Control 6
Mouse testis
NCBI Official Name
Tether containing UBX domain for GLUT4
NCBI Organism
Homo sapiens
Other Product Names
Tether containing UBX domain for GLUT4, Alveolar soft part sarcoma chromosomal region candidate gene 1 protein, Alveolar soft part sarcoma locus, Renal papillary cell carcinoma protein 17, UBX domain-containing protein 9, ASPSCR1, ASPL, RCC17, TUG, UBXD9, UBXN9
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
Curated Selection
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