PIP4K2A Antibody

Product Specifications

Background

Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family.

NCBI Gene ID

5305

Swiss Prot

P48426

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 120-350 of human PIP4K2A (NP_005019.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 46kDa

Fragment

IgG

Symbol

PIP4K2A

Positive Control 2

MCF7

Positive Control 3

Mouse brain

Positive Control 4

Mouse spinal cord

Positive Control 5

Rat brain

NCBI Official Name

Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha

NCBI Organism

Homo sapiens

Other Product Names

PIP4K2A, PI (5) P 4-kinase type II alpha, PIP5KII-alpha, PIP5KIII, PIPK, PtdIns (4) P-5-kinase B isoform, PtdIns (4) P-5-kinase C isoform, PI5P4KA, PIP4KII-alpha, PIP5K2, PIP5KIIalpha, PIP5K2A, PIP5KIIA