NDUFV2 Antibody
Product Specifications
Background
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19.
NCBI Gene ID
4729
Swiss Prot
P19404
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human NDUFV2 (NP_066552.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=22-942
Calculated Molecular Weight
Observed: 27kDa
Fragment
IgG
Symbol
NDUFV2
Positive Control 2
HT-29
Positive Control 3
PC-12
Positive Control 4
Mouse liver
Positive Control 5
Mouse brain
Positive Control 6
Rat liver
NCBI Official Name
NADH:ubiquinone oxidoreductase core subunit V2
NCBI Organism
Homo sapiens
Other Product Names
CI-24k, MC1DN7, NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial, NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa, NADH dehydrogenase ubiquinone flavoprotein 2, mitochondrial, NADH-ubiquinone oxidoreductase 24 kDa subunit, NADH-ubiquinone oxidoreductase flavoprotein 2, complex I 24kDa subunit, complex I, mitochondrial respitory chain, 24 kD subunit, nuclear-encoded mitochondrial NADH-ubiquinone reductase 24Kd subunit
Tested Applications
WB, IHC
Physical Properties
Liquid
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