SIRT6 Antibody
Product Specifications
Background
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
50721
Swiss Prot
Q8N6T7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of mouse SIRT6 (NP_001156902.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 39-45kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SIRT6
Positive Control 2
293T
Positive Control 3
Mouse spleen
Positive Control 4
Mouse stomach
Positive Control 5
A-549
Positive Control 6
LO2
NCBI Official Name
Sirtuin 6
NCBI Organism
Mus musculus
Other Product Names
SIRT6 Antibody: SIR2L6, SIR2L6, NAD-dependent protein deacetylase sirtuin-6, Regulatory protein SIR2 homolog 6
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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