SETDB2 Antibody
Product Specifications
Background
This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
83852
Swiss Prot
Q96T68
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human SETDB2 (NP_001153780.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=22-909
Calculated Molecular Weight
Observed: 82kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SETDB2
Positive Control 2
Mouse thymus
Positive Control 3
Rat heart
NCBI Official Name
SET domain, bifurcated 2
NCBI Organism
Homo sapiens
Other Product Names
Histone-lysine N-methyltransfera, chronic lymphocytic leukemia deletion region gene 8 protein, OTTHUMP00000018418, KMT1F, DKFZp761J1217, DKFZp586I0123, CLLL8, CLLD8, C13orf4, SET domain, bifurcated 2, SETDB2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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